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PAK3 Antikörper (AA 218-247)

PAK3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032142
  • Target Alle PAK3 Antikörper anzeigen
    PAK3
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 218-247
    Reaktivität
    • 70
    • 29
    • 18
    • 3
    Human
    Wirt
    • 65
    • 5
    • 2
    Kaninchen
    Klonalität
    • 67
    • 6
    Polyklonal
    Konjugat
    • 33
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAK3 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 39
    • 31
    • 13
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 218-247 from the human protein was used as the immunogen for this PAK3 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PAK3 Primärantikörper
  • Applikationshinweise
    Titration of the PAK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the PAK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PAK3
    Andere Bezeichnung
    PAK3 (PAK3 Produkte)
    Synonyme
    CDKN1A antikoerper, MRX30 antikoerper, MRX47 antikoerper, OPHN3 antikoerper, PAK3beta antikoerper, bPAK antikoerper, hPAK3 antikoerper, PAK-3 antikoerper, Pak65alpha antikoerper, Pak65beta antikoerper, Stk4 antikoerper, beta-PAK antikoerper, XPak3 antikoerper, bpak antikoerper, cdkn1a antikoerper, mrx30 antikoerper, mrx47 antikoerper, ophn3 antikoerper, pak3 antikoerper, pak3-A antikoerper, pak3beta antikoerper, p21 (RAC1) activated kinase 3 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 3 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog antikoerper, PAK3 antikoerper, Pak3 antikoerper, pak3.L antikoerper
    Hintergrund
    PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.
    UniProt
    O75914
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