PDK4 Antikörper (AA 382-410)
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- Target Alle PDK4 Antikörper anzeigen
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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Bindungsspezifität
- AA 382-410
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDK4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Multiplex Immunohistochemistry (mIHC)
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PDK4 Primärantikörper
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- Applikationshinweise
- Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." in: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).
: "
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Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." in: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).
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- Target
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
- Andere Bezeichnung
- PDK4 (PDK4 Produkte)
- Synonyme
- AV005916 antikoerper, pyruvate dehydrogenase kinase 4 antikoerper, pyruvate dehydrogenase kinase, isoenzyme 4 antikoerper, pdk4 antikoerper, PDK4 antikoerper, Pdk4 antikoerper
- Hintergrund
- PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
- UniProt
- Q16654
- Pathways
- PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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