RAPTOR Antikörper (pSer863)

Produktnummer ABIN3032433

Produktdetails anti-RAPTOR Antikörper

Target: RAPTOR

Bindungsspezifität: pSer863

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAPTOR Antikörper ist unkonjugiert

Applikation: ELISA, Dot Blot (DB)

Aufreinigung: Antigen affinity purified

Immunogen: This phospho-Raptor antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS863 of human Raptor.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the phospho-Raptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the phospho-Raptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RAPTOR

Target: RAPTOR

Andere Bezeichnung: Raptor (RAPTOR Produkte)

Synonyme: KOG1 antikoerper, Mip1 antikoerper, 4932417H02Rik antikoerper, Rap antikoerper, Raptor antikoerper, mKIAA1303 antikoerper, RGD1311784 antikoerper, regulatory associated protein of MTOR complex 1 antikoerper, regulatory associated protein of MTOR, complex 1 antikoerper, RPTOR antikoerper, Rptor antikoerper

Hintergrund: Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.

UniProt: Q8N122

Pathways: Warburg Effekt