Retinoblastoma Protein (Rb) Antikörper (pSer788)
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- Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Bindungsspezifität
- pSer788
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Dot Blot (DB)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- This phospho-Rb antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS788 of human Rb.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product Rb Protein Primärantikörper
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anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein Reaktivität: Human ELISA, IHC, IF, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibodyRb Protein Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibodyRb Protein Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibodyRb Protein Reaktivität: Human, Maus WB, IHC Wirt: Maus Monoclonal 172C1094 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibodyRb Protein Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibodyRb Protein Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) antibodyRb Protein Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 7E4B8 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibodyRb Protein Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Schwein, Pferd, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibodyRb Protein Reaktivität: Human, Maus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibodyRb Protein Reaktivität: Human, Rind (Kuh), Hund, Schwein, Fledermaus, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the phospho-Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,IHC (Paraffin): 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the phospho-Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Andere Bezeichnung
- Retinoblastoma / Rb (Rb Protein Produkte)
- Hintergrund
- RB1 likely acts as a regulator of other genes. It forms a complex with adenovirus E1A and with SV40 large T antigen, acts as a tumor suppressor, and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RB1 is a potent inhibitor of E2F-mediated trans-activation, and also recruits and targets histone methyltransferase SUV39H1 leading to epigenetic transcriptional repression. This protein inhibits the intrinsic kinase activity of TAF1. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB), a congenital malignant tumor that arises from the nuclear layers of the retina. Defects in RB1 are also a cause of bladder cancer and osteogenic sarcoma.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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