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SMAD4 Antikörper (pThr277)

SMAD4 Reaktivität: Human ELISA, IHC, IF, DB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032606
  • Target Alle SMAD4 Antikörper anzeigen
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Bindungsspezifität
    • 12
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr277
    Reaktivität
    • 86
    • 39
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 75
    • 11
    • 1
    Kaninchen
    Klonalität
    • 61
    • 26
    Polyklonal
    Konjugat
    • 53
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD4 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 35
    • 31
    • 23
    • 20
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Dot Blot (DB)
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat
    Aufreinigung
    Antigen affinity purified
    Immunogen
    This phospho-SMAD4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT277 of human SMAD4.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Primärantikörper
  • Applikationshinweise
    Titration of the phospho-SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Dot blot: 1:500,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the phospho-SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Andere Bezeichnung
    SMAD4 (SMAD4 Produkte)
    Hintergrund
    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
    UniProt
    Q13485
    Pathways
    Zellzyklus, Chromatin Binding, Autophagie
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