WEE1 Antikörper (pSer123)

Produktnummer ABIN3029618

Produktdetails anti-WEE1 Antikörper

Target: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Bindungsspezifität: pSer123

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WEE1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Aufreinigung: Antigen affinity purified

Immunogen: This phospho-Wee1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS123 of human Wee1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the phospho-Wee1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the phospho-Wee1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu WEE1

Target: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Andere Bezeichnung: WEE1 (WEE1 Produkte)

Hintergrund: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

UniProt: P30291

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase