Phospholamban Antikörper (AA 1-30)

Produktnummer ABIN3032226

Produktdetails anti-Phospholamban Antikörper

Target: Phospholamban (PLN)

Bindungsspezifität: AA 1-30

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholamban Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for the Phospholamban antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Phospholamban antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Phospholamban antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Phospholamban

Target: Phospholamban (PLN)

Andere Bezeichnung: Phospholamban (PLN Produkte)

Hintergrund: PLB is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

UniProt: P26678

Pathways: Negative Regulation of Transporter Activity