PRKD3 Antikörper (AA 860-890)

Produktnummer ABIN3032381

Produktdetails anti-PRKD3 Antikörper

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Bindungsspezifität: AA 860-890

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Purified

Immunogen: A portion of amino acids 860-890 from the human protein was used as the immunogen for this PKC nu antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PKC nu antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PKC nu antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Andere Bezeichnung: PKC nu (PRKD3 Produkte)

Synonyme: EPK2 antikoerper, PKC-NU antikoerper, PKD3 antikoerper, PRKCN antikoerper, nPKC-NU antikoerper, PRKD3 antikoerper, 4930557O20Rik antikoerper, 5730497N19Rik antikoerper, Pkcnu antikoerper, Prkcn antikoerper, protein kinase D3 antikoerper, PRKD3 antikoerper, prkd3 antikoerper, Prkd3 antikoerper

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

UniProt: O94806