PKM2 Antikörper (AA 116-145)

Produktnummer ABIN3032239

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKM2 in WB, IHC, FACS und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PKM2 Antikörper (AA 116-145) (ABIN3032239)

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Produktdetails anti-PKM2 Antikörper

Bindungsspezifität: AA 116-145

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rabbit, Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 116-145 from the human protein was used as the immunogen for this PKM2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PKM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung: PKM2

Hintergrund: PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

UniProt: P14618

Pathways: Warburg Effekt