PML Antikörper (Sumoylation Site)
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- Target Alle PML Antikörper anzeigen
- PML (Promyelocytic Leukemia (PML))
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Bindungsspezifität
- AA 470-499, Sumoylation Site
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PML Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 470-499 (sumoylation site) from the human protein was used as the immunogen for this PML antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PML Primärantikörper
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anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML Reaktivität: Human WB, IF, ELISA, PLA Wirt: Maus Monoclonal 1D12 unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibodyPML Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB2570 unconjugated
anti-Promyelocytic Leukemia (PML) (AA 300-600) antibodyPML Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (C-Term) antibodyPML Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 411-510) antibodyPML Reaktivität: Human WB, IF, ELISA Wirt: Maus Monoclonal 2B10 unconjugated
anti-Promyelocytic Leukemia (PML) (C-Term) antibodyPML Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML Reaktivität: Human WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 588-637) antibodyPML Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 59-239) antibodyPML Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the PML antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the PML antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- PML (Promyelocytic Leukemia (PML))
- Andere Bezeichnung
- PML (PML Produkte)
- Synonyme
- MYL antikoerper, PP8675 antikoerper, RNF71 antikoerper, TRIM19 antikoerper, 1200009E24Rik antikoerper, AI661194 antikoerper, Trim19 antikoerper, RGD1562602 antikoerper, PML antikoerper, promyelocytic leukemia antikoerper, PML antikoerper, Pml antikoerper
- Hintergrund
- PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
- UniProt
- P29590
- Pathways
- p53 Signalweg, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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