PUMA Antikörper (AA 119-154)
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- Target Alle PUMA (BBC3) Antikörper anzeigen
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Bindungsspezifität
- AA 119-154
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PUMA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 119-154 (BH3 domain) from the human protein was used as the immunogen for this Puma antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product BBC3 Primärantikörper
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anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibodyBBC3 Reaktivität: Human, Ratte, Schwein WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reaktivität: Human WB, FACS, IHC (p), IF Wirt: Kaninchen Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PE)BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal PE
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PerCP)BBC3 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal PerCP
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody (Biotin)BBC3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal Biotin
anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibodyBBC3 Reaktivität: Human, Maus WB, FACS, IHC (p), IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibodyBBC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33714 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 98-152) antibodyBBC3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5D10 unconjugated
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- Applikationshinweise
- Titration of the Puma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Puma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Andere Bezeichnung
- Puma (BBC3 Produkte)
- Synonyme
- BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
- Hintergrund
- PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
- UniProt
- Q9BXH1
- Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity
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