MSK2 Antikörper (AA 322-354)

Produktnummer ABIN3031858

Produktdetails anti-MSK2 Antikörper

Target: MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

Bindungsspezifität: AA 322-354

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Purified

Immunogen: A portion of amino acids 322-354 from the human protein was used as the immunogen for this RSKB antibody (MSK2).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RSKB antibody (MSK2) may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RSKB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MSK2

Target: MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

Andere Bezeichnung: RSKB (MSK2) (RPS6KA4 Produkte)

Synonyme: MSK2 antikoerper, RSK-B antikoerper, 1110069D02Rik antikoerper, 90kDa antikoerper, AI848992 antikoerper, Msk2 antikoerper, mMSK2 antikoerper, ribosomal protein S6 kinase A4 antikoerper, ribosomal protein S6 kinase, polypeptide 4 antikoerper, RPS6KA4 antikoerper, Rps6ka4 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).

UniProt: O75676