RUNX2 Antikörper (AA 445-474)
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- Target Alle RUNX2 Antikörper anzeigen
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Bindungsspezifität
- AA 445-474
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RUNX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 445-474 from the human protein was used as the immunogen for this RUNX2 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RUNX2 Primärantikörper
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human, Ratte WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15321 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human WB, ELISA, IHC, IF, IHC (p) Wirt: Maus Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibodyRUNX2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 1D2 unconjugated
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- Applikationshinweise
- Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the RUNX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Andere Bezeichnung
- RUNX2 (RUNX2 Produkte)
- Hintergrund
- RUNX2 is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. [UniProt]
- UniProt
- Q13950
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