RUNX3 Antikörper (AA 168-197)

Produktnummer ABIN3032505

Produktdetails anti-RUNX3 Antikörper

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Bindungsspezifität: AA 168-197

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RUNX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RUNX3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Andere Bezeichnung: RUNX3 (RUNX3 Produkte)

Synonyme: runxb antikoerper, RUNX3 antikoerper, CBFA3 antikoerper, frrunx3 antikoerper, runx3 antikoerper, aml2 antikoerper, cbfa3 antikoerper, pebp2ac antikoerper, AML2 antikoerper, Cbfa3 antikoerper, Pebp2a3 antikoerper, PEBP2aC antikoerper, runt-related transcription factor 3 antikoerper, runt related transcription factor 3 antikoerper, runt related transcription factor 3 L homeolog antikoerper, runx3 antikoerper, RUNX3 antikoerper, runx3.L antikoerper, Runx3 antikoerper

Hintergrund: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13761