SIRT6 Antikörper (AA 276-305)
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- Target Alle SIRT6 Antikörper anzeigen
- SIRT6 (Sirtuin 6 (SIRT6))
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Bindungsspezifität
- AA 276-305
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIRT6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 276-305 from the human protein was used as the immunogen for this SIRT6 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SIRT6 Primärantikörper
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anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 290-319), (C-Term) antibodySIRT6 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2109 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 Reaktivität: Human, Maus, Ratte, Affe WB, IP, IF Wirt: Maus Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 Reaktivität: Human, Ratte, Hund, Rind (Kuh) WB, IP, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 35-274) antibodySIRT6 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1D8 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 56-105) antibodySIRT6 Reaktivität: Human, Maus, Hund, Affe, Schwein, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the SIRT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Andere Bezeichnung
- SIRT6 (SIRT6 Produkte)
- Hintergrund
- NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity).
- UniProt
- Q8N6T7
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