SLUG Antikörper (AA 98-129)

Produktnummer ABIN3032658

Produktdetails anti-SLUG Antikörper

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Bindungsspezifität: AA 98-129

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLUG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität (Details): Expected species reactivity: Bovine

Aufreinigung: Purified

Immunogen: A portion of amino acids 98-129 from human SNAI2 was used as the immunogen for this SLUG antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SLUG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SLUG

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Andere Bezeichnung: SLUG (SNAI2) (SNAI2 Produkte)

Synonyme: Slug antikoerper, Slugh antikoerper, Snail2 antikoerper, snail family transcriptional repressor 2 antikoerper, snail family zinc finger 2 antikoerper, Snai2 antikoerper

Hintergrund: SLUG/SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress < a href=../search_result.php?search_txt=e cadherin>E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects. [Wiki]

UniProt: O43623