SOCS6 Antikörper (AA 40-69)

Produktnummer ABIN3029048

Produktdetails anti-SOCS6 Antikörper

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Bindungsspezifität: AA 40-69

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 40-69 from the human protein was used as the immunogen for this SOCS6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SOCS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SOCS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6 (SOCS6 Produkte)

Synonyme: CIS-4 antikoerper, CIS4 antikoerper, HSPC060 antikoerper, SOCS-4 antikoerper, SOCS-6 antikoerper, SOCS4 antikoerper, SSI4 antikoerper, STAI4 antikoerper, STATI4 antikoerper, socs6 antikoerper, MGC81477 antikoerper, SOCS6 antikoerper, 1500012M23Rik antikoerper, 5830401B18Rik antikoerper, AI447482 antikoerper, Cis4 antikoerper, Cish4 antikoerper, Socs4 antikoerper, socs6l antikoerper, zgc:64107 antikoerper, wu:fb77f06 antikoerper, suppressor of cytokine signaling 6 antikoerper, suppressor of cytokine signaling 6 L homeolog antikoerper, suppressor of cytokine signaling antikoerper, suppressor of cytokine signaling 6b antikoerper, SOCS6 antikoerper, Socs6 antikoerper, socs6.L antikoerper, socs6 antikoerper, socs6b antikoerper

Hintergrund: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis