SOX7 Antikörper (AA 224-258)

Produktnummer ABIN3032741

Produktdetails anti-SOX7 Antikörper

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Bindungsspezifität: AA 224-258

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 224-258 of the human protein was used as the immunogen for the SOX7 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Andere Bezeichnung: SOX7 (SOX7 Produkte)

Synonyme: sox7-A antikoerper, xSox7 antikoerper, SRY-box 7 antikoerper, SRY (sex determining region Y)-box 7 antikoerper, SRY box 7 antikoerper, SRY-box 7 L homeolog antikoerper, SOX7 antikoerper, Sox7 antikoerper, sox7 antikoerper, sox7.L antikoerper

Hintergrund: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity