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SP1 Antikörper (AA 677-707)

SP1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032701
  • Target Alle SP1 Antikörper anzeigen
    SP1 (Sp1 Transcription Factor (SP1))
    Bindungsspezifität
    • 21
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 677-707
    Reaktivität
    • 88
    • 60
    • 39
    • 11
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 90
    • 13
    • 3
    Kaninchen
    Klonalität
    • 83
    • 23
    Polyklonal
    Konjugat
    • 72
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SP1 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 46
    • 44
    • 36
    • 22
    • 17
    • 14
    • 13
    • 11
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 677-707 from the human protein was used as the immunogen for this SP1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SP1 Primärantikörper
  • Applikationshinweise
    Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the SP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SP1 (Sp1 Transcription Factor (SP1))
    Andere Bezeichnung
    SP1 (SP1 Produkte)
    Hintergrund
    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. [UniProt]
    UniProt
    P08047
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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