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SPHK1 Antikörper (AA 313-343)

SPHK1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032708
  • Target Alle SPHK1 Antikörper anzeigen
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 313-343
    Reaktivität
    • 101
    • 48
    • 43
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 92
    • 9
    • 1
    Kaninchen
    Klonalität
    • 88
    • 14
    Polyklonal
    Konjugat
    • 51
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPHK1 Antikörper ist unkonjugiert
    Applikation
    • 69
    • 40
    • 23
    • 18
    • 13
    • 13
    • 12
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SPHK1 Primärantikörper
  • Applikationshinweise
    Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the SPHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Andere Bezeichnung
    SPHK1 (SPHK1 Produkte)
    Synonyme
    CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper
    Hintergrund
    SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
    UniProt
    Q9NYA1
    Pathways
    VEGF Signaling
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