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SUV39H1 Antikörper (N-Term)

SUV39H1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029052
  • Target Alle SUV39H1 Antikörper anzeigen
    SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
    Bindungsspezifität
    • 17
    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 67
    • 17
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 59
    • 8
    Kaninchen
    Klonalität
    • 59
    • 8
    Polyklonal
    Konjugat
    • 23
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SUV39H1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 34
    • 13
    • 13
    • 12
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Purified
    Immunogen
    N-terminal purified recombinant protein was used as the immunogen for the SUV39H1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SUV39H1 Primärantikörper
  • Applikationshinweise
    Titration of the SUV39H1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the SUV39H1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
    Andere Bezeichnung
    SUV39H1 (SUV39H1 Produkte)
    Synonyme
    H3-K9-HMTase 1 antikoerper, KMT1A antikoerper, MG44 antikoerper, SUV39H antikoerper, AI852103 antikoerper, AL022883 antikoerper, DXHXS7466e antikoerper, mIS6 antikoerper, RGD1565028 antikoerper, kmt1a antikoerper, suv39h antikoerper, fe02c04 antikoerper, suv39h1 antikoerper, wu:fe02c04 antikoerper, zgc:101027 antikoerper, fe47h06 antikoerper, wu:fb18a10 antikoerper, wu:fe47h06 antikoerper, zgc:136593 antikoerper, suppressor of variegation 3-9 homolog 1 antikoerper, suppressor of variegation 3-9 homolog 1 (Drosophila) antikoerper, suppressor of variegation 3-9 homolog 1 L homeolog antikoerper, suppressor of variegation 3-9 homolog 1a antikoerper, suppressor of variegation 3-9 homolog 1b antikoerper, SUV39H1 antikoerper, Suv39h1 antikoerper, suv39h1.L antikoerper, suv39h1a antikoerper, suv39h1b antikoerper
    Hintergrund
    Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.
    UniProt
    O43463
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