SYVN1 Antikörper (AA 586-617)
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- Target Alle SYVN1 Antikörper anzeigen
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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Bindungsspezifität
- AA 586-617
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SYVN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 586-617 from the human protein was used as the immunogen for this SYVN1 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SYVN1 Primärantikörper
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anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 586-617), (C-Term) antibody
SYVN1 Reaktivität: Human, Maus WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB4822 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodyVerified SYVN1 Reaktivität: Human, Ratte WB, ELISA, FACS, IF Wirt: Ziege Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 531-617) antibodySYVN1 Reaktivität: Human, Maus WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 338-487) antibodySYVN1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 58-88), (N-Term) antibodySYVN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB5086 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 1-617) antibodySYVN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 Reaktivität: Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Kaninchen, Fledermaus, Affe, Zebrafisch (Danio rerio), Hamster, Xenopus laevis IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 238-318) antibodySYVN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4H4 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 501-550) antibodySYVN1 Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the SYVN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:200-1000,IHC (Paraffin): 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the SYVN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
- Andere Bezeichnung
- SYVN1 (HRD1) (SYVN1 Produkte)
- Hintergrund
- HRD1/SYVN1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of SYVN1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. It is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects.
- UniProt
- Q86TM6
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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