tau Antikörper (AA 677-707)
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- Target Alle tau Antikörper anzeigen
- tau (tau Protein)
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Bindungsspezifität
- AA 677-707
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser tau Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Bovine
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product tau Primärantikörper
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- Applikationshinweise
- Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the TAU antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- tau (tau Protein)
- Andere Bezeichnung
- tau (tau Produkte)
- Synonyme
- DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper
- Hintergrund
- TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]
- UniProt
- P10636
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