TBK1 Antikörper (AA 8-35)
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- Target Alle TBK1 Antikörper anzeigen
- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Bindungsspezifität
- AA 8-35
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TBK1 Primärantikörper
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- Applikationshinweise
- Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Tbk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Andere Bezeichnung
- Tbk1 (TBK1 Produkte)
- Synonyme
- nak antikoerper, t2k antikoerper, TBK1 antikoerper, wu:fk70c05 antikoerper, zgc:136548 antikoerper, NAK antikoerper, T2K antikoerper, 1200008B05Rik antikoerper, AI462036 antikoerper, AW048562 antikoerper, TANK binding kinase 1 L homeolog antikoerper, TANK binding kinase 1 antikoerper, TANK-binding kinase 1 antikoerper, tbk1.L antikoerper, TBK1 antikoerper, tbk1 antikoerper, Tbk1 antikoerper
- Hintergrund
- Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
- UniProt
- Q9WUN2
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
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