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TBP Antikörper (AA 210-239)

TBP Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029099
  • Target Alle TBP Antikörper anzeigen
    TBP (TATA Box Binding Protein (TBP))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-239
    Reaktivität
    • 75
    • 45
    • 43
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 57
    • 18
    • 2
    Kaninchen
    Klonalität
    • 59
    • 18
    Polyklonal
    Konjugat
    • 45
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TBP Antikörper ist unkonjugiert
    Applikation
    • 59
    • 25
    • 14
    • 13
    • 10
    • 10
    • 10
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Kreuzreaktivität (Details)
    Expected species reactivity: Bovine, Chicken, Mouse, Primate, Xenopus, Zebrafish
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 210-239 from the human protein was used as the immunogen for this TBP antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TBP Primärantikörper
  • Applikationshinweise
    Titration of the TBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the TBP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TBP (TATA Box Binding Protein (TBP))
    Andere Bezeichnung
    TBP (TBP Produkte)
    Synonyme
    GTF2D antikoerper, GTF2D1 antikoerper, HDL4 antikoerper, SCA17 antikoerper, TFIID antikoerper, Gtf2d antikoerper, fd20h06 antikoerper, si:zc101n13.2 antikoerper, wu:fd20h06 antikoerper, zgc:66213 antikoerper, TBP1 antikoerper, TBP antikoerper, tbp antikoerper, CG9874 antikoerper, Dmel\\CG9874 antikoerper, RBP antikoerper, TBP38 antikoerper, TFIIDtau antikoerper, TfIID antikoerper, dTBP antikoerper, dTFIID antikoerper, dTbp antikoerper, dtbp antikoerper, gtf2d antikoerper, gtf2d1 antikoerper, sca17 antikoerper, tfiid antikoerper, tfiidtau antikoerper, xtbp antikoerper, tbp-a antikoerper, tbp-b antikoerper, TATA-box binding protein antikoerper, TATA box binding protein antikoerper, TATA binding protein antikoerper, TATA-box binding protein L homeolog antikoerper, TATA-box-binding protein antikoerper, TATA-box binding protein S homeolog antikoerper, TBP antikoerper, Tbp antikoerper, tbp antikoerper, tbp.L antikoerper, tbp.S antikoerper
    Hintergrund
    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
    UniProt
    P20226
    Pathways
    WNT Signalweg
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