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TICAM1 Antikörper (AA 115-143)

TICAM1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029184
  • Target Alle TICAM1 Antikörper anzeigen
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-143
    Reaktivität
    • 25
    • 9
    • 3
    • 2
    Human, Maus
    Wirt
    • 22
    • 4
    • 3
    Kaninchen
    Klonalität
    • 25
    • 4
    Polyklonal
    Konjugat
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TICAM1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 115-143 from the human protein was used as the immunogen for this TICAM1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TICAM1 Primärantikörper
  • Applikationshinweise
    Titration of the TICAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the TICAM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Andere Bezeichnung
    TICAM1 (TICAM1 Produkte)
    Synonyme
    IIAE6 antikoerper, MyD88-3 antikoerper, PRVTIRB antikoerper, TICAM-1 antikoerper, TRIF antikoerper, AW046014 antikoerper, AW547018 antikoerper, trif antikoerper, toll like receptor adaptor molecule 1 antikoerper, toll-like receptor adaptor molecule 1 antikoerper, TICAM1 antikoerper, Ticam1 antikoerper, ticam1 antikoerper
    Hintergrund
    Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
    UniProt
    Q8IUC6
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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