TLE1 Antikörper (N-Term)

Produktnummer ABIN3029204

Produktdetails anti-TLE1 Antikörper

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Aufreinigung: Antigen affinity purified

Immunogen: This TLE1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 187-221 amino acids from the N-terminal region of human TLE1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TLE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TLE1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Andere Bezeichnung: TLE1 (TLE1 Produkte)

Synonyme: ESG antikoerper, ESG1 antikoerper, GRG1 antikoerper, C230057C06Rik antikoerper, Estm14 antikoerper, Grg1 antikoerper, Tle4l antikoerper, TLE1 antikoerper, transducin like enhancer of split 1 antikoerper, transducin-like enhancer protein 1 antikoerper, transducin-like enhancer of split 1 antikoerper, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antikoerper, TLE1 antikoerper, Smp_150080 antikoerper, Tle1 antikoerper, LOC100354911 antikoerper, LOC100524475 antikoerper, LOC100061341 antikoerper

Hintergrund: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

UniProt: Q04724

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom