TSG101 Antikörper (AA 1-30)

Produktnummer ABIN3029402

Produktdetails anti-TSG101 Antikörper

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Bindungsspezifität: AA 1-30

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this TSG101 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: TSG101 (TSG101 Produkte)

Hintergrund: TSG101 is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. [UniProt]

UniProt: Q99816