Tuberin Antikörper (AA 1776-1805)

Produktnummer ABIN3029331

Produktdetails anti-Tuberin Antikörper

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Bindungsspezifität: AA 1776-1805

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tuberin Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1776-1805 from the human protein was used as the immunogen for this Tuberin antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Tuberin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Tuberin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Andere Bezeichnung: Tuberin (TSC2 Produkte)

Synonyme: TSC2 antikoerper, fc16b02 antikoerper, tuberin antikoerper, wu:fc16b02 antikoerper, LAM antikoerper, TSC4 antikoerper, Nafld antikoerper, Tcs2 antikoerper, Rc antikoerper, TSC complex subunit 2 antikoerper, tuberin antikoerper, hypothetical protein antikoerper, tuberous sclerosis 2 antikoerper, TSC2 antikoerper, LOC5569538 antikoerper, tsc2 antikoerper, PGTG_00159 antikoerper, Tsc2 antikoerper

Hintergrund: Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

UniProt: P49815

Pathways: RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus