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WEE1 Antikörper (AA 202-230)

WEE1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029617
  • Target Alle WEE1 Antikörper anzeigen
    WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
    Bindungsspezifität
    • 20
    • 15
    • 12
    • 11
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 202-230
    Reaktivität
    • 94
    • 53
    • 42
    • 2
    Human, Maus
    Wirt
    • 104
    • 5
    • 2
    Kaninchen
    Klonalität
    • 109
    • 2
    Polyklonal
    Konjugat
    • 44
    • 9
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser WEE1 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 50
    • 28
    • 28
    • 23
    • 16
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Rat
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 202-230 from the mouse protein was used as the immunogen for this Wee1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product WEE1 Primärantikörper
  • Applikationshinweise
    Titration of the Wee1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Wee1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
    Andere Bezeichnung
    Wee1 (WEE1 Produkte)
    Synonyme
    WEE1A antikoerper, WEE1hu antikoerper, ATWEE1 antikoerper, F22D16.3 antikoerper, F22D16_3 antikoerper, WEE1 kinase homolog antikoerper, WEE1-KINASE antikoerper, WEE1 antikoerper, Xe-Wee1B antikoerper, XeWee1B antikoerper, wee1-b antikoerper, wee1a antikoerper, wee2-a antikoerper, xe-wee1a antikoerper, xwee1 antikoerper, wee1 antikoerper, wee1b antikoerper, wee1hu antikoerper, xwee2 antikoerper, GB19689 antikoerper, Wee1A antikoerper, fa20h03 antikoerper, wu:fa20h03 antikoerper, zgc:136514 antikoerper, WEE1 G2 checkpoint kinase antikoerper, Wee1 kinase antikoerper, WEE1-like kinase antikoerper, WEE1 G2 checkpoint kinase S homeolog antikoerper, wee1 homolog antikoerper, WEE1 homolog 2 antikoerper, wee1-like protein kinase antikoerper, WEE 1 homolog 1 (S. pombe) antikoerper, M phase inhibitor protein kinase Wee1 antikoerper, WEE1 antikoerper, Wee1 antikoerper, wee1.S antikoerper, wee1-a antikoerper, wee2 antikoerper, LOC551677 antikoerper, wee1 antikoerper
    Hintergrund
    Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur (By similarity).
    UniProt
    P47810
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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