Calprotectin Antikörper

Produktnummer ABIN4956353

Produktdetails anti-Calprotectin Antikörper

Target: Calprotectin (S100A8/A9)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calprotectin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: purified

Immunogen: human recombinant protein

Klon: 69-6-1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Dilution: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.23

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Details zu Calprotectin

Target: Calprotectin (S100A8/A9)

Andere Bezeichnung: calprotectin- S100A8/A9 complex (S100A8/A9 Produkte)

Hintergrund: Calprotectin is a functional heterocomplex of small EF hand calcium-binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via it's binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammatory conditions.

Molekulargewicht: 45 kDa

Pathways: S100 Proteine