HNRNPC Antikörper (N-Term)

Produktnummer ABIN497942

Produktdetails anti-HNRNPC Antikörper

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Bindungsspezifität: AA 1-142, N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes hnRNP-C1/C2/HNRNPC (1-152).
Cellular Localization: Nucleus.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse (100 %), Rat (100 %), Bovine (100 %) and Rabbit (92 %)Species reactivity (tested):Human.

Aufreinigung: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 142 of hnRNP-C1/C2.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/100-1/250. Positive Controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.79 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Andere Bezeichnung: HnRNP-C1/C2 / HNRNPC (HNRNPC Produkte)

Hintergrund: HnRNP-C1/C2 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.Synonyms: HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1 / hnRNP C2

Gen-ID: 3183, 9606

UniProt: P07910