Dystroglycan Antikörper (Internal Region)
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- Target Alle Dystroglycan (DAG1) Antikörper anzeigen
- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Dystroglycan Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Sequenz
- C-HVGKHEYFMH ATDK
- Spezifität
- This antibody is expected to recognize both the precursor and the mature Alpha-Dystroglycan, but not the mature Beta-Dystroglycan.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat. - Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide from the internal region of the protein sequence according to NP_004384.3. Genename: DAG1
- Top Product
- Discover our top product DAG1 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: Detection Limit: 1/128000. Western blot: 0.2-0.6 μg/mL. Detects a band of Approx 100 kDa in Human Skeletal Muscle lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
- Andere Bezeichnung
- Dystroglycan (DAG1 Produkte)
- Synonyme
- LOC398500 antikoerper, dag1 antikoerper, MGC53537 antikoerper, 156DAG antikoerper, A3a antikoerper, AGRNR antikoerper, DAG antikoerper, MDDGC7 antikoerper, MDDGC9 antikoerper, DAG1 antikoerper, RAB7 antikoerper, dg antikoerper, a3a antikoerper, dag antikoerper, agrnr antikoerper, 156dag antikoerper, D9Wsu13e antikoerper, DG antikoerper, Dp427 antikoerper, Dp71 antikoerper, CG18250 antikoerper, CT41273 antikoerper, DmDG antikoerper, Dmel\\CG18250 antikoerper, atu antikoerper, dgn antikoerper, dys antikoerper, GB14967 antikoerper, APOJ antikoerper, CLI antikoerper, RATTRPM2B antikoerper, SGP-2 antikoerper, SGP2 antikoerper, SP-40 antikoerper, SP40 antikoerper, TRPM-2 antikoerper, TRPM2B antikoerper, Trpm2 antikoerper, Trpmb antikoerper, Ala-1 antikoerper, H9/25 antikoerper, Ly-27 antikoerper, Ly-6 antikoerper, Ly27 antikoerper, wu:fb83d06 antikoerper, wu:fi25f06 antikoerper, wu:fi37b08 antikoerper, zgc:109786 antikoerper, DystroGlycaN antikoerper, dystroglycan 1 L homeolog antikoerper, dystroglycan 1 antikoerper, dystroglycan 1 S homeolog antikoerper, Dystroglycan antikoerper, dystroglycan antikoerper, clusterin antikoerper, lymphocyte antigen 6 complex antikoerper, dgn-1 antikoerper, dag1.L antikoerper, dgn-2 antikoerper, dgn-3 antikoerper, DAG1 antikoerper, dag1.S antikoerper, Dag1 antikoerper, dag1 antikoerper, Dg antikoerper, LOC408826 antikoerper, Clu antikoerper, Ly6 antikoerper
- Hintergrund
- Dystroglycans are essential elements of the neuromuscular junction (NMJ). The gene for dystroglycan is expressed as a precursor protein that is post translationally cleaved into a 156 kDa extracellular peripheral membrane protein called alpha Dystroglycan and a 43 kDa transmembrane protein, beta Dystroglycan. The latter protein contains a PPxY motif that promotes binding to WW domain containing proteins, such as utrophin and dystrophin.Synonyms: DAG1, Dystrophin-associated glycoprotein 1
- Gen-ID
- 1605
- NCBI Accession
- NP_004384
- UniProt
- Q14118
- Pathways
- Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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