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PMP22 Antikörper
PMP22
Reaktivität: Human, Ratte, Maus
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-PMP22 Antikörper
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Target
Alle PMP22 Antikörper anzeigen
PMP22
(Peripheral Myelin Protein 22 (PMP22))
Reaktivität
Alle Reaktivitäten für PMP22 Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für PMP22 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PMP22 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PMP22 Antikörper
Dieser PMP22 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PMP22 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This detects endogenous levels of GAS3 protein.
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography using epitope-specific immunogen
Reinheit
> 95 % (by SDS-PAGE)
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Discover our top product PMP22 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Western blot: 1: 500 - 1: 1000. immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu PMP22
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Target
PMP22
(Peripheral Myelin Protein 22 (PMP22))
Andere Bezeichnung
PMP22 (PMP22 Produkte )
Synonyme
CMT1A antikoerper, CMT1E antikoerper, DSS antikoerper, GAS-3 antikoerper, HMSNIA antikoerper, HNPP antikoerper, Sp110 antikoerper, 22kDa antikoerper, Gas-3 antikoerper, Tr antikoerper, trembler antikoerper, pmp22 antikoerper, wu:fa04d03 antikoerper, wu:fa08d03 antikoerper, MGC80653 antikoerper, PMP22 antikoerper, MGC69407 antikoerper, id:ibd2630 antikoerper, wu:fb81f09 antikoerper, zgc:136919 antikoerper, peripheral myelin protein 22 antikoerper, peripheral myelin protein 22a antikoerper, peripheral myelin protein 22 S homeolog antikoerper, peripheral myelin protein 22b antikoerper, PMP22 antikoerper, Pmp22 antikoerper, pmp22a antikoerper, pmp22.S antikoerper, pmp22 antikoerper, pmp22b antikoerper
Hintergrund
PMP 22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.Synonyms: GAS-3, GAS3, Growth arrest-specific protein 3, PMP-22, Peripheral myelin protein 22
Molekulargewicht
approx. 22 kDa
Gen-ID
5376
NCBI Accession
NP_000295
UniProt
Q01453
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