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CD19 Antikörper

CD19 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498242
  • Target Alle CD19 Antikörper anzeigen
    CD19 (CD19 Molecule (CD19))
    Reaktivität
    • 293
    • 166
    • 41
    • 29
    • 19
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Maus
    Wirt
    • 185
    • 130
    • 57
    • 4
    Kaninchen
    Klonalität
    • 257
    • 115
    • 2
    Polyklonal
    Konjugat
    • 127
    • 25
    • 22
    • 22
    • 19
    • 10
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CD19 Antikörper ist unkonjugiert
    Applikation
    • 265
    • 117
    • 74
    • 70
    • 52
    • 52
    • 23
    • 21
    • 14
    • 14
    • 10
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody detects endogenous levels of CD19 protein.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography using epitope-specific immunogen
    Reinheit
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product CD19 Primärantikörper
  • Applikationshinweise
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CD19 (CD19 Molecule (CD19))
    Andere Bezeichnung
    CD19 (CD19 Produkte)
    Hintergrund
    CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin- like domains. CD19 is selectively expressed on the cell surface of B lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B cell development and through terminal differentiation of B cells into plasma cells. CD19 forms functional complexes with B lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B cell development.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    Molekulargewicht
    approx. 61 kDa
    Gen-ID
    930
    NCBI Accession
    NP_001761
    UniProt
    P15391
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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