CD19 Antikörper
-
- Target Alle CD19 Antikörper anzeigen
- CD19 (CD19 Molecule (CD19))
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CD19 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects endogenous levels of CD19 protein.
- Kreuzreaktivität (Details)
-
Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography using epitope-specific immunogen
- Reinheit
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product CD19 Primärantikörper
-
-
- Applikationshinweise
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- Target
- CD19 (CD19 Molecule (CD19))
- Andere Bezeichnung
- CD19 (CD19 Produkte)
- Hintergrund
- CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin- like domains. CD19 is selectively expressed on the cell surface of B lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B cell development and through terminal differentiation of B cells into plasma cells. CD19 forms functional complexes with B lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B cell development.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
- Molekulargewicht
- approx. 61 kDa
- Gen-ID
- 930
- NCBI Accession
- NP_001761
- UniProt
- P15391
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
-