CK1 epsilon Antikörper

Produktnummer ABIN498317

Produktdetails anti-CK1 epsilon Antikörper

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CK1 epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Casein Kinase Iε protein. (region surrounding Pro301)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Andere Bezeichnung: Casein Kinase I epsilon (CSNK1E Produkte)

Synonyme: CKIepsilon antikoerper, HCKIE antikoerper, CKIe antikoerper, ck1-epsilon antikoerper, ck1epsilon antikoerper, hckie antikoerper, dco antikoerper, fj38c01 antikoerper, wu:fj38c01 antikoerper, wu:fj62a04 antikoerper, zgc:77310 antikoerper, AI426939 antikoerper, AI551861 antikoerper, AW457082 antikoerper, CK1epsilon antikoerper, KC1epsilon antikoerper, tau antikoerper, ckie antikoerper, CSNK1E antikoerper, Csnk1e antikoerper, CKI-epsilon antikoerper, 0538/13 antikoerper, 0915/10 antikoerper, 1396/02 antikoerper, 1447/01 antikoerper, 1460/09 antikoerper, CG2048 antikoerper, CK1delta/epsilon antikoerper, DBT antikoerper, DBT/CK1epsilon antikoerper, DCO antikoerper, DCO/CKIe antikoerper, Dbt antikoerper, Dco antikoerper, Dco/CK1 antikoerper, Dmel\CG2048 antikoerper, dCKIepsilon antikoerper, dbt antikoerper, dco-1 antikoerper, ddbt antikoerper, l(3)S053813 antikoerper, l(3)S144701 antikoerper, l(3)dco antikoerper, l(3)dco-1 antikoerper, l(3)discs overgrown antikoerper, l(3)discs overgrown-1 antikoerper, l(3)j3B9 antikoerper, l(3)rK215 antikoerper, casein kinase 1 epsilon antikoerper, casein kinase 1, epsilon antikoerper, casein kinase 1 epsilon L homeolog antikoerper, casein kinase I isoform epsilon antikoerper, casein kinase I epsilon antikoerper, casein kinase I antikoerper, LOC400927-CSNK1E readthrough antikoerper, discs overgrown antikoerper, CSNK1E antikoerper, csnk1e antikoerper, Csnk1e antikoerper, csnk1e.L antikoerper, LOC443240 antikoerper, NAEGRDRAFT_82890 antikoerper, LOC100407384 antikoerper, LOC100523244 antikoerper, LOC100607246 antikoerper, LOC100727500 antikoerper, LOC400927-CSNK1E antikoerper, dco antikoerper

Hintergrund: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CKI-epsilon, CKIe, CSNK1E

Molekulargewicht: approx. 47 kDa

Gen-ID: 1454

NCBI Accession: NP_001885

UniProt: P49674

Pathways: Hedgehog Signalweg, M Phase