TIAL1 Antikörper (Internal Region)

Produktnummer ABIN499121

Produktdetails anti-TIAL1 Antikörper

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TIAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-SPEITTEDIK SAFAP

Spezifität: This antibody is expected to recognize both isoforms (NP_003243.1, NP_001029097.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the Internal region of Human TIAL1 (NP_003243.1 and NP_001029097.1) Genename: TIAL1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/64000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line K562.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TIAL1

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Andere Bezeichnung: TIAL1 (TIAL1 Produkte)

Hintergrund: TIA1 is a member of an RNA binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.Synonyms: Nucleolysin TIAR, TIA-1-related protein

Molekulargewicht: 43.4 kDa (NP_001029097.1)

Gen-ID: 7073

NCBI Accession: NP_003243

UniProt: Q01085