PSMA4 Antikörper (Internal Region)

Produktnummer ABIN499149

Produktdetails anti-PSMA4 Antikörper

Target: PSMA4 (Proteasome Subunit alpha 4 (PSMA4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PSMA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-SDANVLTNEL R

Spezifität: This antibody is expected to recognize both reported isoforms (NP_002780.1 and NP_001096138.1).

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human, Mouse Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002780.1 and NP_001096138.1 Genename: PSMA4

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 1-3 μg/mL. This antibody detects a band of approx. 28 kDa in lysates of cell line K562and in lysates of Human Tonsil and Human Peripheral Blood Mononucleocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PSMA4

Target: PSMA4 (Proteasome Subunit alpha 4 (PSMA4))

Andere Bezeichnung: PSMA4 (PSMA4 Produkte)

Synonyme: wu:fe05d10 antikoerper, zgc:56176 antikoerper, DDBDRAFT_0204055 antikoerper, DDBDRAFT_0214953 antikoerper, DDB_0204055 antikoerper, DDB_0214953 antikoerper, C9 antikoerper, HC9 antikoerper, HsT17706 antikoerper, PSC9 antikoerper, proteasome subunit alpha 4 antikoerper, proteasome subunit alpha 4 S homeolog antikoerper, proteasome subunit alpha type 4 antikoerper, 20S proteasome subunit alpha-4 antikoerper, proteasome (prosome, macropain) subunit, alpha type 4 antikoerper, psma4 antikoerper, psma4.S antikoerper, PSMA4 antikoerper, CNF01860 antikoerper, psmA4 antikoerper, Psma4 antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA4 is a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: HC9, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, PSC9, Proteasome component C9, Proteasome subunit L, Proteasome subunit alpha type-4

Molekulargewicht: 29.5kDa (NP_002780.1)

Gen-ID: 5685

NCBI Accession: NP_001096137

UniProt: P25789

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA