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AIFM3 Antikörper (N-Term)

AIFM3 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499241
  • Target Alle AIFM3 Antikörper anzeigen
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIFM3 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to AIFM3.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    AIFM3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human AIFM3.
    Isotyp
    IgG
    Top Product
    Discover our top product AIFM3 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: AIFM3 antibody can be used for the detection of AIFM3 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Abstract
    AIFM3 Produkte
    Synonyme
    nfrl-A antikoerper, MGC84340 antikoerper, AIFM3 antikoerper, LOC100150876 antikoerper, 2810401C16Rik antikoerper, AI840249 antikoerper, Aifl antikoerper, RGD1306028 antikoerper, AIFL antikoerper, apoptosis inducing factor, mitochondria associated 3 L homeolog antikoerper, apoptosis inducing factor, mitochondria associated 3 antikoerper, apoptosis-inducing factor, mitochondrion-associated 3 antikoerper, aifm3.L antikoerper, AIFM3 antikoerper, aifm3 antikoerper, Aifm3 antikoerper
    Hintergrund
    Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.Synonyms: AIFL, Apoptosis-inducing factor 3
    Gen-ID
    150209
    UniProt
    Q96NN9
    Pathways
    Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
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