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ANAPC7 Antikörper (C-Term)

ANAPC7 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499303
  • Target Alle ANAPC7 Antikörper anzeigen
    ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))
    Bindungsspezifität
    • 6
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 11
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 11
    Dieser ANAPC7 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    APC7 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APC7.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: APC7 antibody can be used for detection of APC7 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))
    Andere Bezeichnung
    APC7 / ANAPC7 (ANAPC7 Produkte)
    Synonyme
    DDBDRAFT_0184417 antikoerper, DDBDRAFT_0235159 antikoerper, DDB_0184417 antikoerper, DDB_0235159 antikoerper, si:ch211-127h20.1 antikoerper, APC7 antikoerper, AW545589 antikoerper, T7F6.26 antikoerper, T7F6_26 antikoerper, anaphase promoting complex subunit 7 antikoerper, anaphase promoting complex subunit 7 L homeolog antikoerper, tetratricopeptide repeat (TPR)-containing protein antikoerper, anapc7 antikoerper, ANAPC7 antikoerper, anapc7.L antikoerper, Anapc7 antikoerper, APC7 antikoerper
    Hintergrund
    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.Synonyms: Anaphase-promoting complex subunit 7, Cyclosome subunit 7
    Gen-ID
    51434
    NCBI Accession
    NP_057322
    UniProt
    Q4KMX6
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