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ARL6IP1 Antikörper (C-Term)

ARL6IP1 Reaktivität: Human, Maus WB, EIA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499337
  • Target Alle ARL6IP1 Antikörper anzeigen
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Bindungsspezifität
    • 14
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 38
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 34
    • 4
    Kaninchen
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARL6IP1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    Human ARMER / ARL6IP / AIP1 (C-Terminus) Peptide
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: ARMER antibody can be used for detection of ARMER at 0.5 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Andere Bezeichnung
    ARL6IP1 (ARL6IP1 Produkte)
    Synonyme
    arl6ip antikoerper, MGC56593 antikoerper, zgc:56593 antikoerper, zgc:77873 antikoerper, ARL6IP antikoerper, aip1 antikoerper, armer antikoerper, ARL6IP1 antikoerper, MGC85055 antikoerper, MGC139614 antikoerper, DKFZp459O112 antikoerper, AIP1 antikoerper, ARMER antikoerper, AIP-6 antikoerper, AL022945 antikoerper, AU042858 antikoerper, Aip-1 antikoerper, Arl6ip antikoerper, C85138 antikoerper, mKIAA0069 antikoerper, ADP-ribosylation factor-like 6 interacting protein 1 antikoerper, ADP ribosylation factor like GTPase 6 interacting protein 1 antikoerper, ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog antikoerper, ADP-ribosylation factor like GTPase 6 interacting protein 1 antikoerper, arl6ip1 antikoerper, ARL6IP1 antikoerper, arl6ip1.L antikoerper, Arl6ip1 antikoerper
    Hintergrund
    Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12 (2), other caspases such as caspase-9 are also thought to be activated following ER stress (3). Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, KIAA0069
    Gen-ID
    23204
    UniProt
    Q15041
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