BANF1 Antikörper (N-Term)

Produktnummer ABIN499409

Produktdetails anti-BANF1 Antikörper

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BANF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to BANF1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: BANF1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human BANF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: BANF1 antibody can be used for detection of BANF1 at 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Andere Bezeichnung: BANF1 (BANF1 Produkte)

Hintergrund: Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BAF also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BAF will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BAF is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.Synonyms: BAF, BCRG1, Barrier-to-autointegration factor, Breakpoint Cluster Region Protein 1

Gen-ID: 8815

UniProt: O75531