SH3GLB1 Antikörper (C-Term)

Produktnummer ABIN499465

Produktdetails anti-SH3GLB1 Antikörper

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3GLB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This anitbody reacts to BIF.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: BIF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BIF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western BLot: BIF antibody can be used for the detection of BIF at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Andere Bezeichnung: Endophilin-B1 (SH3GLB1 Produkte)

Synonyme: im:5777505 antikoerper, wu:fa08f03 antikoerper, wu:fb13e12 antikoerper, MGC79086 antikoerper, sh3glb1 antikoerper, wu:fc55h11 antikoerper, wu:fj98d09 antikoerper, AA409932 antikoerper, AI314629 antikoerper, AU015566 antikoerper, Bif-1 antikoerper, mKIAA0491 antikoerper, PPP1R70 antikoerper, dJ612B15.2 antikoerper, SH3-domain GRB2-like endophilin B1b antikoerper, SH3 domain GRB2 like, endophilin B1 S homeolog antikoerper, SH3 domain GRB2 like, endophilin B1 antikoerper, SH3 domain containing GRB2 like, endophilin B1 antikoerper, SH3-domain GRB2-like endophilin B1a antikoerper, SH3-domain GRB2-like B1 (endophilin) antikoerper, SH3 domain -containing GRB2-like endophilin B1 antikoerper, SH3 domain containing GRB2 like endophilin B1 antikoerper, sh3glb1b antikoerper, sh3glb1.S antikoerper, sh3glb1 antikoerper, SH3GLB1 antikoerper, sh3glb1a antikoerper, Sh3glb1 antikoerper

Hintergrund: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes.. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of BIF promoted HeLa cell colony formation in soft agar, it may have a role in the suppression of cancer progression. At least two isoforms of BIF are known to exist.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

Gen-ID: 51100

UniProt: Q9Y371

Pathways: Autophagie