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BRSK1 Antikörper (C-Term)

BRSK1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499499
  • Target Alle BRSK1 Antikörper anzeigen
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 51
    • 31
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 73
    Kaninchen
    Klonalität
    • 72
    • 1
    Polyklonal
    Konjugat
    • 21
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BRSK1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 38
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to BRSK1.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    BRSK1 antibody was raised against a 28 amino acid peptide from near the carboxy terminus of human BRSK1.
    Isotyp
    IgG
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    Discover our top product BRSK1 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: BRSK1 antibody can be used for detection of BRSK1 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    Andere Bezeichnung
    BRSK1 (BRSK1 Produkte)
    Synonyme
    BRSK1 antikoerper, hSAD1 antikoerper, Gm1100 antikoerper, SAD-B antikoerper, SADB antikoerper, RGD1563268 antikoerper, Sad-b antikoerper, BR serine/threonine kinase 1 antikoerper, BRSK1 antikoerper, Brsk1 antikoerper
    Hintergrund
    BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B
    Gen-ID
    84446
    UniProt
    Q8TDC3
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