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CALHM1 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CALHM1 in WB, IF, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN499519

Kurzübersicht für CALHM1 Antikörper (N-Term) (ABIN499519)

Target

Alle CALHM1 Antikörper anzeigen
CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))

Reaktivität

  • 23
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 23
Kaninchen

Klonalität

  • 23
Polyklonal

Konjugat

  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CALHM1 Antikörper ist unkonjugiert

Applikation

  • 21
  • 13
  • 13
  • 7
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, Mouse, Rat.

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    17 amino acid peptide near the amino terminus of Human CALHM1

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: CALHM1 antibody can be used for detection of CALHM1 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))

    Andere Bezeichnung

    CALHM1 / FAM26C

    Hintergrund

    Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-b (Ab) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Ab levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.Synonyms: Calcium homeostasis modulator protein 1

    Gen-ID

    255022

    NCBI Accession

    NP_001001412

    UniProt

    Q8IU99
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