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5-Methylcytosine Antikörper (AbBy Fluor® 750)

WB, FACS, IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN4995770
  • Target
    5-Methylcytosine
    Reaktivität
    Bitte anfragen
    Wirt
    • 21
    • 9
    • 3
    Kaninchen
    Klonalität
    • 23
    • 10
    Polyklonal
    Konjugat
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 750
    Applikation
    • 19
    • 15
    • 12
    • 10
    • 9
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Kreuzreaktivität (Details)
    5 MethylCytosine
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated 5 MethylCytosine
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    5-Methylcytosine
    Andere Bezeichnung
    5 MethylCytosine
    Substanzklasse
    Chemical
    Hintergrund

    Synonyms: 5-Methyl Cytidine, 5 m C, 5 mC, 5 me C, 5 Me Cytidine, 5 MeCyd, 5 Methyl Cytidine, 5 MethylCytosine, 5-mC, 5-Me Cytidine, 5-Methyl-Cytosine, 5-MethylCytidine.

    Background: Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.

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