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Adenylosuccinate Lyase Antikörper (AA 185-280) (AbBy Fluor® 680)

ADSL Reaktivität: Human, Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN4996123
  • Target Alle Adenylosuccinate Lyase (ADSL) Antikörper anzeigen
    Adenylosuccinate Lyase (ADSL)
    Bindungsspezifität
    • 14
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 185-280
    Reaktivität
    • 44
    • 20
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 40
    • 4
    Kaninchen
    Klonalität
    • 41
    • 2
    Polyklonal
    Konjugat
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Adenylosuccinate Lyase Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 17
    • 12
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Adenylosuccinate Lyase (ADSL)
    Andere Bezeichnung
    Adenylosuccinate Lyase (ADSL Produkte)
    Synonyme
    fi60b04 antikoerper, zgc:56061 antikoerper, wu:fi60b04 antikoerper, MGC53383 antikoerper, MGC69239 antikoerper, adsL antikoerper, F15C21.8 antikoerper, F15C21_8 antikoerper, AMPS antikoerper, ASASE antikoerper, ASL antikoerper, Adl antikoerper, Asl antikoerper, purB antikoerper, adenylosuccinate lyase antikoerper, adenylosuccinate lyase L homeolog antikoerper, adenylosuccinase; ASL antikoerper, Adenylosuccinate lyase antikoerper, L-Aspartase-like family protein antikoerper, ADSL antikoerper, adsl antikoerper, adsl.L antikoerper, ASL antikoerper, purB antikoerper, purB,adsL antikoerper, Mrub_2293 antikoerper, MMAH_RS02975 antikoerper, Arnit_0089 antikoerper, Mesil_1058 antikoerper, Slip_0597 antikoerper, Trad_2452 antikoerper, Deba_0652 antikoerper, Toce_1174 antikoerper, Acear_2324 antikoerper, Igag_0272 antikoerper, Saut_2156 antikoerper, Fbal_1996 antikoerper, Ndas_2434 antikoerper, Ilyop_0196 antikoerper, Lbys_2961 antikoerper, MFER_RS02920 antikoerper, Palpr_2192 antikoerper, Calni_0061 antikoerper, Ftrac_3746 antikoerper, AT1G36280 antikoerper, Olsu_1764 antikoerper, Adsl antikoerper
    Hintergrund

    Synonyms: Adenylosuccinase, Adenylosuccinate lyase, ADSL, AMPS, ASase, ASL, PUR8_HUMAN.

    Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

    Pathways
    Ribonucleoside Biosynthetic Process
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