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CENPO Antikörper (Center)

CENPO Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499615
  • Target Alle CENPO Antikörper anzeigen
    CENPO (Centromere Protein O (CENPO))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 27
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 27
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CENPO Antikörper ist unkonjugiert
    Applikation
    • 20
    • 15
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    CENPO antibody was raised against a 16 amino acid peptide from near the center of human CENPO.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: CENPO antibody can be used for detection of CENPO at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    CENPO (Centromere Protein O (CENPO))
    Andere Bezeichnung
    CENP-O (CENPO Produkte)
    Synonyme
    cenpo antikoerper, MGC144960 antikoerper, CENPO antikoerper, MAJ23.70 antikoerper, MAJ23_70 antikoerper, zgc:171667 antikoerper, CENP-O antikoerper, ICEN-36 antikoerper, MCM21R antikoerper, 2810429O05Rik antikoerper, 8430427C03Rik antikoerper, D12Ertd482e antikoerper, centromere protein O antikoerper, cenpo antikoerper, CENPO antikoerper, AT5G10710 antikoerper, Cenpo antikoerper
    Hintergrund
    Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Synonyms: CENPO, Centromere protein O, ICEN36, Interphase centromere complex protein 36
    Gen-ID
    79172
    NCBI Accession
    NP_077298
    UniProt
    Q9BU64
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