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AFAP1L2 Antikörper (AbBy Fluor® 680)

AFAP1L2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN4996187
  • Target Alle AFAP1L2 Antikörper anzeigen
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    Reaktivität
    • 20
    • 19
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AFAP1L2 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human AFAP1L2
    Isotyp
    IgG
    Top Product
    Discover our top product AFAP1L2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    Andere Bezeichnung
    AFAP1L2 (AFAP1L2 Produkte)
    Synonyme
    KIAA1914 antikoerper, XB130 antikoerper, AU041783 antikoerper, C86904 antikoerper, mKIAA1914 antikoerper, RGD1310668 antikoerper, actin filament associated protein 1 like 2 antikoerper, actin filament associated protein 1-like 2 antikoerper, AFAP1L2 antikoerper, Afap1l2 antikoerper
    Hintergrund

    Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.

    Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

    Pathways
    EGFR Signaling Pathway
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