BIRC2 Antikörper (C-Term)

Produktnummer ABIN499623

Produktdetails anti-BIRC2 Antikörper

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: C-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human cIAP (C-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: cIAP antibody can be used for the detection of c-IAP at 1 to 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Andere Bezeichnung: IAP2 / BIRC2 (BIRC2 Produkte)

Synonyme: API1 antikoerper, HIAP2 antikoerper, Hiap-2 antikoerper, MIHB antikoerper, RNF48 antikoerper, c-IAP1 antikoerper, cIAP1 antikoerper, Api2 antikoerper, rIAP1 antikoerper, IAP1 antikoerper, ITA antikoerper, AW146227 antikoerper, Api1 antikoerper, Birc3 antikoerper, HIAP1 antikoerper, IAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, MIHC antikoerper, cIAP2 antikoerper, mcIAP1 antikoerper, ciap-1 antikoerper, birc3 antikoerper, api1 antikoerper, birc2 antikoerper, c-iap1 antikoerper, ciap1 antikoerper, hiap-2 antikoerper, hiap2 antikoerper, mihb antikoerper, rnf48 antikoerper, baculoviral IAP repeat containing 2 antikoerper, baculoviral IAP repeat-containing 2 antikoerper, baculoviral IAP repeat containing 2 L homeolog antikoerper, BIRC2 antikoerper, Birc2 antikoerper, birc2 antikoerper, birc2.L antikoerper

Hintergrund: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspasesSynonyms: API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1

Gen-ID: 329

NCBI Accession: NP_001157

UniProt: Q13490

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades